13 Best MSM Supplements for Inflammation and Joint Pain Relief (2024)

Table of Contents
In This Review Overview Expert’s Advice On Joint Pain Our Top Picks Best MSM Supplements For Joint Pain JointXL Plus | Best For Joint Health Definite Improvement. ProJoint Plus | Best Joint Supplement Happy with the product! Micro Ingredients | Best MSM Powder For Hair Growth Ideal Support for Healthy Joint Function. Pure Encapsulations MSM | Best MSM Joint Supplement Great Product! NOW MSM Powder | Best MSM Powder This works. Doctor’s Best MSM | Doctors Best MSM Supplement Happy joints. BulkSupplements MSM | Best For Healthy Skin Love this stuff. Jarrow Formulas MSM | Best For Optimal Health Works. Kala Health MSM Pure | Best For Chronic Joint Issues Excellent Product! Life Extension MSM 1000 mg | Best For Joint Health FINALLY SOMETHING THAT WORKS. Horbaach MSM Supplement | Best For Immune Function This is a good product. Move Free Joint Health | Best Glucosamine for Arthritis This stuff is amazing! Osteo Bi Flex Triple Strength | Best Pills For Joint Pain Works for joint pain and soft tissue repair. What Is MSM Supplement? Thing To Consider Before Buying MSM Supplement Purity and Quality Dosage Ingredients Form Allergies and Sensitivities Brand Reputation and Customer Reviews What Are The Benefits Of Methylsulfonylmethane Supplements? Can MSM Supplements Help You Relieve Joint Pain? Product Comparison Frequently Asked Questions Q. How to use MSM supplements for reducing joint-related symptoms? Q. Is it safe to use MSM supplements? Q. What are the dangers of MSM? Q. What do MSM supplements do to the brain? Q. When should I take MSM supplements? Final Thought Why Trust CHD? Was this article helpful? Louise Mooney, RN, B.A.(Hons) 6 Sources

In This Review

  • Overview
  • Expert’s Advice
  • Our Top Picks
  • 13 Best MSM Supplements
  • What Is It?
  • Thing To Consider
  • Benefits
  • How Can It Help?
  • Product Comparison
  • FAQs
  • Final Thought
  • Why Trust CHD?

Overview

Arthritis, injuries, strains, infection, inflammation and many other factors can affect joints; causing a person to experience joint pain, tenderness, inflammation and other such symptoms that might make life harder than before.

While there are many cases where joint pain is mild, causing little restriction in a person’s life, some people experience more severe levels of pain, inflammation and other symptoms that cause them to experience disability and disruption every day.

With the significant effect that joint pain and related symptoms can have on a person’s overall lifestyle and abilities, treatment is essential for reducing the daily problems these symptoms can bring.

There are medication and pharmaceutical options available to relieve joint aches,but there are several risk factors involved in using them. However, there are also alternative remedies available that may help to provide effective results for joint management without exposing the body to any harmful risks.

Today, we want to introduce our readers to a particular ingredient that has been clinically proven to effectively provide positive results when used as a remedy to treat joint pain and inflammation.

The substance we would like to focus on is called methylsulfonylmethane, more commonly referred to as MSM. In addition to describing how MSM can be useful, we will discuss how other natural substances (such as Chondroitin Sulphate and Glucosamine) can be used in pain reduction and inflammation, which can improve the quality of a person’s life.
Furthermore, we would like to introduce our readers to some highly effective MSM substances which can be purchased for fast and effective results.

Expert’s Advice On Joint Pain

Dr. David Felson, an associate professor of medicine and epidemiology at Boston University School of Medicine, claims that treating joint pain needs a whole-body approach. According to Felson, your lifestyle plays a significant role in reducing joint pain. It is best to lose weight so that it does not put pressure on joints, causing joint pain.

You should also engage in muscle strength exercises on a routine basis. Strong muscles can help support and stretch the joints. An anti-inflammatory diet can also help reduce inflammation. Rich foods in omega-3 fatty acids have anti-inflammatory properties.

Our Top Picks

  • JointXL Plus – Best For Joint Health
  • ProJoint Plus – Best Joint Supplement
  • Micro Ingredients MSM – Best MSM Powder For Hair Growth
  • Pure Encapsulations MSM – Best MSM Joint Supplement
  • NOW MSM Powder – Best MSM Powder
  • Doctor’s Best – Doctors Best MSM Supplement
  • BulkSupplements MSM Powder – Best For Healthy Skin
  • Jarrow Formulas MSM – Best For Optimal Health
  • Kala Health MSM Pure Vegetarian – Best For Chronic Joint Issues
  • Life Extension MSM 1000 mg – Best For Joint Health
  • Horbaach MSM Supplement – Best For Immune Function
  • Move Free Joint Health – Best Glucosamine for Arthritis
  • Osteo Bi Flex Triple Strength – Best Pills For Joint Pain

Best MSM Supplements For Joint Pain

We have discussed the numerous benefits that MSM has to offer a person who suffers from joint pain, inflammation, and other symptoms that arthritis may be causing.

Let’s take an in-depth look at some of the best MSM supplements that you can buy to help you better cope with your arthritis-related symptoms.

JointXL Plus | Best For Joint Health

13 Best MSM Supplements for Inflammation and Joint Pain Relief (1)

JointXL Plus

13 Best MSM Supplements for Inflammation and Joint Pain Relief (2)

(4.9/5) 541 REVIEWS

$59.00

$54.00OFFICIAL WEBSITE

PRODUCT HIGHLIGHTS

  • Doctor Recommended
  • 100% Money Back Gurantee
  • Powerful Proven Results
  • Laboratory Tested Ingredients
  • Proven Rapid Relief Within 7 Days
  • Form: Capsules
  • Quantity: 60 Capsules
  • Brand: JointXL Plus
  • Dosage: 6 Capsules Per Day
  • Ingredients: Boswellia Serrata, Bromelain, MSM, Glucosamine, Methionine
  • Usage: Enhances Comfort, Mobility & Flexibility
  • Safety: Doctor Recommended, 100% Natural
  • Refund Policy: 60-Day
  • Company Info: store@jointxlplus.com, +1-(800)-986-9271

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Definite Improvement.13 Best MSM Supplements for Inflammation and Joint Pain Relief (4)

“I’ve been living with knee pain for over 12 years, so I was skeptical about trying another supplement. However, after using JointXL Plus for just one week, I noticed a significant improvement. The pain and swelling in my knees have reduced, and I’m no longer relying on painkillers. I even tried a cheaper alternative with similar ingredients, but my knee pain returned within a week. JointXL Plus has truly made a difference, and I highly recommend it!” – Ronny. E

READ FULL REVIEWS

JointXL Plus is a leading supplement designed to alleviate joint pain, reduce inflammation, and enhance flexibility. With a potent blend of natural ingredients like Boswellia Serrata, Bromelain, MSM, Glucosamine, and Methionine, it targets joint issues comprehensively. Whether you suffer from arthritis-related discomfort or general joint stiffness, Joint XLPlus aims to improve mobility and overall joint health. Boswellia Serrata, a key ingredient in JointXL Plus, has been extensively studied for its anti-inflammatory properties.

Research from the National Institutes of Health highlights Boswellia’s effectiveness in reducing joint pain and inflammation by inhibiting inflammatory proteins. This natural extract supports JointXL Plus’s claim to provide relief from joint discomfort through scientifically validated mechanisms.

JointXL Plus is formulated to support joint health by reducing swelling, improving flexibility, and providing antioxidant support. Its blend of ingredients works synergistically to alleviate pain and enhance joint function. The supplement is manufactured in a GMP-certified facility, ensuring high quality and safety standards. It is suitable for individuals looking to manage arthritis symptoms, prevent joint damage, and improve overall joint mobility.
Check For Best Deal

ProJoint Plus | Best Joint Supplement

13 Best MSM Supplements for Inflammation and Joint Pain Relief (6)

ProJoint Plus

13 Best MSM Supplements for Inflammation and Joint Pain Relief (7)

(4.9/5) 61 REVIEWS

PRODUCT HIGHLIGHTS

  • High-Quality Ingredients
  • 100% Herbal Extracts
  • Reputable Manufacturer
  • Made In The USA
  • Money Back Gaurantee
  • Form: Capsule
  • Quantity: 60 Capsules
  • Brand: Vitapost
  • Dosage: 3 Capsules Daily
  • Ingredients: Chondroitin Sulfate, Methylsulfonylmethane(MSM), & Bromelain
  • Usage: Supports Joint and Cartilage Health
  • Safety: No Prescription Required, FDA Registered Facilities
  • Refund Policy: 30-Day
  • Company Info: Vita Balance Inc, 7400 Beaufont Springs Drive, Suite 300, Richmond, Virginia 23225, United States, +1-888-455-9995, support@vitabalance.net

13 Best MSM Supplements for Inflammation and Joint Pain Relief (8)

Happy with the product!13 Best MSM Supplements for Inflammation and Joint Pain Relief (9)

“I’m taking ProJoint Plus because I have bone on bone pain in my hips from osteoarthritis. I’ve been on a carnivore/keto diet for several months to see if it can help. I didn’t have enough pills to take the supplements first. Would it be beneficial if I received another bottle to take the 6 capsules a day for 2 weeks even though I have almost finished my first bottle? I was encouraged by the reviews I read. I would appreciate your assistance and feedback. Thank you very much.” – Heather

READ FULL REVIEWS

Projoint Plus is a dietary supplement designed to support joint health and mobility. It contains a blend of natural ingredients that have been scientifically proven to reduce joint pain, increase flexibility, and support cartilage health.

13 Best MSM Supplements for Inflammation and Joint Pain Relief (11)According to Journal Osteoarthritis and Cartilage [1], “Chondroitin Sulfate was effective in reducing pain and improving joint function in patients with hand osteoarthritis. The study also discovered that chondroitin sulphate was safe.”13 Best MSM Supplements for Inflammation and Joint Pain Relief (12)

One of the key ingredients in Projoint Plus is MSM (Methylsulfonylmethane), which is a natural sulfur formula found in many foods. MSM has been shown to have anti-inflammatory properties that can help reduce joint pain and stiffness. It also supports the health of connective tissues such as tendons, ligaments, and cartilage. It is manufactured in an FDA-registered facility using good manufacturing practices (GMP) to ensure quality and purity. The supplement is free of artificial colours, flavours, and preservatives and is suitable for vegetarians and vegans.

Check For Best Deal

13 Best MSM Supplements for Inflammation and Joint Pain Relief (13)

Micro Ingredients | Best MSM Powder For Hair Growth

13 Best MSM Supplements for Inflammation and Joint Pain Relief (14)

Micro Ingredients MSM Powder

13 Best MSM Supplements for Inflammation and Joint Pain Relief (15)

(3.3/5) 343 REVIEWS

$21.95AMAZON

PRODUCT SPECIFICATIONS

  • Form: Powder
  • Quantity: 1 Kg
  • Brand: Micro Ingredients
  • Dosage: 1 Scoop Per Day
  • Ingredients: Methylsulfonylmethane, Vitamin C
  • Usage: Support Ultimate Joint Function and Collagen Formation
  • Safety: Non-GMO, Organic Ingredients, Gluten Free, Soy Free
  • Refund Policy: 30-Day
  • Company Info: info@microingredients.com

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Ideal Support for Healthy Joint Function.

13 Best MSM Supplements for Inflammation and Joint Pain Relief (17)
“My knees have improved significantly since I began using Micro Ingredients MSM Powder. I used to hear bone scraping against bone in my knees when I got out of a chair. Thanks to this product, my knees are now lubricated and stronger. I take this every day, and you will see results if you do the same for as long as I have. My knees haven’t made a peep since I started using this product.” – Amber S.

Micro Ingredients MSM Powder is a dietary supplement that contains methylsulfonylmethane (MSM), a natural compound found in plants, animals, and humans. MSM is a form of sulfur that is important for many biological processes in the body, including the maintenance of healthy joints, skin, and hair.

MSM is known for its anti-inflammatory properties and is often used to reduce joint pain and stiffness. It is also used to improve the health of skin and hair as it’s an essential part of collagen, a protein that gives skin and hair strength and elasticity. It also helps the immune system function by reducing inflammation and oxidative stress in the body.

13 Best MSM Supplements for Inflammation and Joint Pain Relief (18)According to Journal Arthritis Research & Therapy[2], “Vitamin C supplementation was associated with a significant reduction in pain and stiffness among patients with rheumatoid arthritis. Research suggests the vitamin may ease pain, reduce inflammation, and protect against cartilage damage associated with osteoarthritis (OA).”13 Best MSM Supplements for Inflammation and Joint Pain Relief (19)

Micro Ingredients MSM Powder is made from pure MSM crystals that are derived from natural sources. The powder is free from additives, fillers, and preservatives, making it a pure and potent source of MSM.

Official Website

13 Best MSM Supplements for Inflammation and Joint Pain Relief (20)

Pure Encapsulations MSM | Best MSM Joint Supplement

PRODUCT SPECIFICATIONS

  • Form: Capsules
  • Quantity: 360 Capsules
  • Brand: Pure Encapsulations
  • Dosage: 2 Capsules Per Day
  • Ingredients: Methylsulfonylmethane(MSM)
  • Usage: Support Joint, Immune and Respiratory Health
  • Safety: High Quality Vegan Ingredients, Gluten Free, GMO Free
  • Refund Policy: 30-Day
  • Company Info: Pure Encapsulations, LLC, 490 Boston Post Road, Sudbury, MA 01776, +1-(800) 753-2277,
    InternationalBusiness@purecaps.com

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Great Product!

13 Best MSM Supplements for Inflammation and Joint Pain Relief (24)
“I have been taking MSM by Pure Encapsulations for about 17 months,faithfully,twice each day. I have no joint pain, and the health of my hair and nails has improved drastically. I am very happy with this product and love the large amount! Thus, the bottle lasts me at least 4 months.” – Maira S.

Pure Encapsulations MSM is a joint pain relief supplement that contains methylsulfonylmethane (MSM), that helps in the formation and maintenance of connective tissue, including cartilage, collagen, and elastin.

Pure Encapsulations MSM capsules are a safe and effective supplement for reducing inflammation, improving joint health, and promoting healthy skin, hair, and nails. The capsules support the body’s natural detoxification processes, helping to remove toxins and waste products from the body.

It is formulated with high-quality, pure MSM that has been rigorously tested for potency and purity. Each capsule contains 850mg of MSM, and it is free from wheat, gluten, eggs, peanuts, magnesium stearate, hydrogenated fat, artificial sweeteners, and colors.

Official Website

13 Best MSM Supplements for Inflammation and Joint Pain Relief (25)

NOW MSM Powder | Best MSM Powder

13 Best MSM Supplements for Inflammation and Joint Pain Relief (26)

NOW MSM Powder

13 Best MSM Supplements for Inflammation and Joint Pain Relief (27)

(3.5/5) 367 REVIEWS

$16.53AMAZON

$17.56WALMART

PRODUCT SPECIFICATIONS

  • Form: Powder
  • Quantity: 454gm
  • Brand: NOW
  • Dosage: 2 Teaspoon Twice in a Day
  • Ingredients: Methylsulfonylmethane(MSM)
  • Usage: Supports Healthy Cartilage, Joint Sulfur For Connective Tissue
  • Safety: Non-GMO, Dairy Free, Soy Free, Nut Free
  • Refund Policy: 30-Day
  • Company Info: 244 Knollwood Drive, Bloomingdale, IL 60108, +1-888-669-3663

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This works.

13 Best MSM Supplements for Inflammation and Joint Pain Relief (29)
“It does not taste good, but it works! I am in my 50s and was losing a lot of hair. I found that my hair has stopped falling out and my skin is better. I am now starting my second bottle, and it’s part of my daily morning regimen! I take a teaspoon with a small amount of cold water and down it. I am getting used to the bitter taste and don’t mind it anymore. I had tried capsules before but found that this powder seems to work a lot better.”– ANNE

MSM Powder by NOW Foods is a sulfur-containing compound that is naturally present in very small amounts in fruits, vegetables, grains, animal products, and some algae. MSM powder works by providing sulfur, an essential nutrient needed to build many tissues in the body. Sulfur is a component of collagen, which is essential for maintaining healthy joints, skin, and hair. MSM is also believed to have anti-inflammatory properties, which may help reduce pain and swelling in the body.

NOW Foods MSM powder is known for its potential health benefits, including reducing inflammation, improving joint health, and promoting healthy skin, hair, and nails. It is made from high-quality ingredients and produced in a cGMP-certified facility, ensuring its purity and potency. The supplement is gluten-free, non-GMO, and vegan-friendly, making it a suitable choice for a wide range of dietary needs.

Official Website

13 Best MSM Supplements for Inflammation and Joint Pain Relief (30)

Doctor’s Best MSM | Doctors Best MSM Supplement

13 Best MSM Supplements for Inflammation and Joint Pain Relief (31)

Doctor’s Best MSM with OptiMSM

13 Best MSM Supplements for Inflammation and Joint Pain Relief (32)

(3.6/5) 463 REVIEWS

$22.98AMAZON

$21.55WALMART

PRODUCT SPECIFICATIONS

  • Form: Capsules
  • Quantity: 360 Capsules
  • Brand: Doctor’s Best
  • Dosage: 3 Capsules Per Day
  • Ingredients: Methylsulfonylmethane(MSM), Gelatin
  • Usage: Support Joint Comfort and Mobility, Support Antioxidant Defenses
  • Safety: Non-GMO, Gluten Free
  • Refund Policy: 60-Day
  • Company Info: NA

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Happy joints.

13 Best MSM Supplements for Inflammation and Joint Pain Relief (34)
“This supplement is an ingredient that helps keep my joints happy and healthy. While the pills are rather large, I have no problem swallowing them. And I believe this is a quality product. I have recently started lifting weights again and was concerned about how this would feel on my joints. I believe this product is helping me navigate a changing workout routine with minimal pain.”– Renny

Doctors Best MSM is a high-quality, purified form of MSM (methylsulfonylmethane), backed by numerous clinical studies for safety and efficacy. MSM is a natural Sulfur compound that helps support the formation of healthy connective tissues. MSM provides sulfur and is often called “nature’s beauty mineral”. Sulfur restores collagen production, which supports healthy skin and is a building block of keratin, an essential protein for improving skin, hair, and nails.

13 Best MSM Supplements for Inflammation and Joint Pain Relief (35)According to study[3], “Collagen supplements, such as gelatin, can help with joint pain. They also observed that it can strengthen joints by increasing cartilage density. Gelatin also contains lysine, which helps in bone strength.”13 Best MSM Supplements for Inflammation and Joint Pain Relief (36)

MSM is a natural sulfur that helps form the antioxidants N-acetylcysteine and glutathione and serves as a key structural nutrient in healthy joints. It is gluten-free and non-GMO, making it suitable for a wide range of dietary needs. Doctor’s Best MSM supplement is also free of unnecessary additives and fillers, ensuring that you are getting a pure and potent product.

Official Website

13 Best MSM Supplements for Inflammation and Joint Pain Relief (37)

BulkSupplements MSM | Best For Healthy Skin

13 Best MSM Supplements for Inflammation and Joint Pain Relief (38)

BulkSupplements MSM Powder

13 Best MSM Supplements for Inflammation and Joint Pain Relief (39)

(3.1/5) 2193 REVIEWS

$9.96AMAZON

$9.96WALMART

PRODUCT SPECIFICATIONS

  • Form: Powder
  • Quantity: 1Kg
  • Brand: BULKSUPPLEMENTS.COM
  • Dosage: 2 Teaspoon Twice in a Day
  • Ingredients: Methylsulfonylmethane(MSM), Bovine Gelatin
  • Usage: Support Joint Comfort, Promote Healthy Skin and Hair
  • Safety: Gluten Free
  • Refund Policy: 30-Day
  • Company Info: USA, +1-702 425-7638, cs@bulksupplements.com

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Love this stuff.

13 Best MSM Supplements for Inflammation and Joint Pain Relief (41)
“MSM is great for my joints. Lots of years playing soccer involved sliding tackles. Soccer players know what those are. And it’s hard on the knees, on the wrist, and even on the hips. But my knees are where I wanted the most relief from pain, and I got it with this supplement. Not only does it help with the pain, but it actually helps rebuild the joint. So I no longer have to wear a knee brace after using this. And I don’t have the pain or inflammation. Love MSM. “– Lorraine Y.

BulkSupplements MSM Powder is a joint pain relief supplement that contains methylsulfonylmethane (MSM), an organic sulfur compound that helps with tissue formation, joint health, and digestion. It can also aid in muscle recovery after exercise. Plus, this powder is 97% pure, meaning it is of the highest quality. MSM powder contains an essential chemical that helps support the joints, immune function, skin, and hair.In addition, anMSM supplement alsocontributes to healthydigestion andaidsin recovery after strenuous exercise.

This MSM supplement does not contain any fillers, additives, or artificial flavors. And it is free of gluten, soy, dairy, and added sugar, making it ideal for people with dietary restrictions.

Official Website

13 Best MSM Supplements for Inflammation and Joint Pain Relief (42)

Jarrow Formulas MSM | Best For Optimal Health

PRODUCT SPECIFICATIONS

  • Form: Capsules
  • Quantity: 200 Capsules
  • Brand: Jarrow Formulas
  • Dosage: 2 Capsules Per Day
  • Ingredients: Methylsulfonylmethane(MSM), Magnesium Stearate
  • Usage: Strengthens Joints, Promote Optimal Health
  • Safety: Gluten Free, Vegan, Nut-free, Wheat-free
  • Refund Policy: 60-Day
  • Company Info: USA, +1-(800) 726-0886, orders@vytalogy.com

13 Best MSM Supplements for Inflammation and Joint Pain Relief (45)

Works.

13 Best MSM Supplements for Inflammation and Joint Pain Relief (46)
“Jarrow Formulas MSM has anti-inflammatory and antioxidant effects and helps produce collagen. That in turn helps support joint health, the formation of healthy connective tissues, mobility, helps maintain skin elasticity, and helps have strong nails and thick hair. So it has a lot of benefits. Take them daily to see improvement. Very high-quality product.”– Laira K.

Jarrow Formulas MSM is an organic source of bioavailable sulfur. Sulfur is an antioxidant mineral found in major structural tissues of the body,such as cartilage. The sulfur from MSM is used to produce glycosaminoglycans (or mucopolysaccharides) present in proteoglycans, such as chondroitin sulfate, dermatan sulfate and hyaluronic acid[4]. These sulfur-containing glycosaminoglycans are found in high concentrations in connective tissues, including joint cartilage, skin, & collagen.

Jarrow Formulas MSM is formulated to provide 1000mg of MSM per capsule. It is manufactured in a cGMP (current good manufacturing practice) facility to ensure quality and purity. The product is also third-party tested for purity and potency, and the results of these tests are available on the Jarrow Formulas website. The capsules are vegetarian and free from common allergens such as wheat, gluten, soybeans, dairy, eggs, fish and shellfish, peanuts, and tree nuts. The product is also non-GMO & does not contain any artificial colours or flavors.

Official Website

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Kala Health MSM Pure | Best For Chronic Joint Issues

13 Best MSM Supplements for Inflammation and Joint Pain Relief (48)

Kala Health MSM Pure Vegetarian Capsule

13 Best MSM Supplements for Inflammation and Joint Pain Relief (49)

(3.4/5) 2 REVIEWS

$19.95AMAZON

PRODUCT SPECIFICATIONS

  • Form: Capsules
  • Quantity: 120 Capsules
  • Brand: Kala Health
  • Dosage: 4 Capsules Per Day
  • Ingredients: Methylsulfonylmethane(MSM), Hypromellose
  • Usage: Helps Prevent Chronic Joint Issues
  • Safety: Non-GMO, Gluten Free, Allergen Free
  • Refund Policy: 30-Day
  • Company Info: 607 East Main Street, Suite 3, Meriden, CT 06450, +1-(508) 495-4034, sales@kalahealth.com

13 Best MSM Supplements for Inflammation and Joint Pain Relief (50)

Excellent Product!

13 Best MSM Supplements for Inflammation and Joint Pain Relief (51)
“I like the fact that this is pure MSM, with no fillers or flow agents. I also like the fact that the capsule is made of gelatin. Too many supplements use cellulose capsules. The cellulose they use in most veggie caps is actually a synthetic compound that starts out as wood cellulose but is chemically altered, so it is no longer a natural substance.”– Linda M.

Kala Health MSM Pure Vegetarian Capsules is a specially-designed elongated VegiCaps that delivers a full one-gram (1000 mg) dose. It is formulated with OptiMSM MSM Coarse Powder, the purest, safest, and most consistent quality MSM, backed by numerous pre-clinical and clinical studies. MSM is the organic form of naturally occurring Sulfur. Kala Health MSM Pure Vegetarian Capsule is a high-quality dietary supplement that may provide a range of potential health benefits for overall joint health and range of motion, may improve joint stress recovery time, and may prevent chronic joint issues.

MSM Pure undergoes a proprietary multi-stage distillation process that ensures a 99.9% pure product that has been third-party tested to meet our stringent product specifications. It is the only GRAS-designated, Kosher & Halal-certified, non-GMO, gluten-free, allergen-free, non-shellfish-derived, vegan MSM with extensive toxicology data.

Official Website

13 Best MSM Supplements for Inflammation and Joint Pain Relief (52)

Life Extension MSM 1000 mg | Best For Joint Health

13 Best MSM Supplements for Inflammation and Joint Pain Relief (53)

Life Extension MSM 1000 mg Capsules

13 Best MSM Supplements for Inflammation and Joint Pain Relief (54)

(3.6/5) 85 REVIEWS

$12.27AMAZON

PRODUCT SPECIFICATIONS

  • Form: Capsules
  • Quantity: 100 Capsules
  • Brand: Life Extension
  • Dosage: 3 Capsules Per Day
  • Ingredients: Methylsulfonylmethane(MSM), Gelatin
  • Usage: Promotes Joint Comfort and Health
  • Safety: Gluten Free, Non-GMO
  • Refund Policy: NA
  • Company Info: 3600 West Commercial Boulevard, Fort Lauderdale, FL 33309, +1-888-895-4771, legal@LifeExtension.com

13 Best MSM Supplements for Inflammation and Joint Pain Relief (55)

FINALLY SOMETHING THAT WORKS.

13 Best MSM Supplements for Inflammation and Joint Pain Relief (56)
“I am so impressed with the MSM supplement! This powerful supplement has greatly improved my joint health and reduced pain and stiffness throughout my body. I love that it’s made with natural, high-quality ingredients and is free from any harmful additives. Overall, I highly recommend this supplement to anyone looking for a safe and effective way to support their joint health and overall well-being.”– Marry

Life Extension MSM 1000 mg is a dietary supplement that provides 1000mg of MSM per serving. It is designed to support joint health and mobility, promote healthy hair and skin, and provide antioxidant support. MSM, a naturally occurring sulfur compound in the body, reportedly improves joint health and reduces muscle soreness. It could boost immunity, fight inflammation, and reduce oxidative damage.

MSM provides essential raw materials for your body to create new cells and restore damaged organs and tissues. It may also boost collagen formation and improve circulation to ensure the health of your connective tissues. It may improve your skin and hair health by reducing signs of aging, stretch marks, acne, hair loss, and dandruff.

Official Website

13 Best MSM Supplements for Inflammation and Joint Pain Relief (57)

Horbaach MSM Supplement | Best For Immune Function

13 Best MSM Supplements for Inflammation and Joint Pain Relief (58)

Horbaach MSM Supplement

13 Best MSM Supplements for Inflammation and Joint Pain Relief (59)

(3.5/5) 167 REVIEWS

$9.99AMAZON

PRODUCT SPECIFICATIONS

  • Form: Capsules
  • Quantity: 240 Capsules
  • Brand: Horbäach
  • Dosage: 2 Capsules Per Day
  • Ingredients: Methylsulfonylmethane(MSM), Gelatin
  • Usage: Supports Immune Function, Supports Joint Pain
  • Safety: GMO Free, Gluten Free
  • Refund Policy: NA
  • Company Info: Horbaach, 2110 Smithtown Ave, Ronkonkoma, NY 11779-7347, +1-800-945-8802,
    customerservice@horbaach.com

13 Best MSM Supplements for Inflammation and Joint Pain Relief (60)

This is a good product.

13 Best MSM Supplements for Inflammation and Joint Pain Relief (61)
“Too good to be true, but it rally works. My hair has grown and thickened since I’ve started this supplement. And I tried it because I had problems with thinning falling hair, to the point I taught I am going to become bald. The change is unbelievable, after just a few months ! I am taking 2-3 capsules a day.”– Renny

Horbaach MSM 1500mg Supplement is a dietary supplement that contains a high dose of methylsulfonylmethane (MSM)[5], Methylsulfonylmethane, commonly known as MSM, is a sulfur-containing compound and one of the most common minerals found in plants, animals, and humans! It’s found only in low concentration in animal-based foods, which is why supplementation is important for those needing additional support.

Each serving of Horbaach MSM 1500mg Supplement provides 1500mg of MSM, which is a higher dose than the standard MSM supplement. The capsules are made with vegetarian-friendly materials and are free from gluten, dairy, soy, and artificial colors and flavors. It’s gluten-free and non-GMO with no preservatives, a high-quality formula for a balanced routine.

Official Website

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Move Free Joint Health | Best Glucosamine for Arthritis

13 Best MSM Supplements for Inflammation and Joint Pain Relief (63)

Move Free Joint Health Advanced Plus MSM

13 Best MSM Supplements for Inflammation and Joint Pain Relief (64)

(3.6/5) 187 REVIEWS

$21.99AMAZON

$23.69WALMART

PRODUCT SPECIFICATIONS

  • Form: Coated Tablets
  • Quantity: 120 Coated Tablets
  • Brand: Move Free
  • Dosage: 3 Tablets Per Day
  • Ingredients: Glucosamine Hydrochloride, Methylsulfonylmethane(MSM), Uniflex, Chondroitin Sulfate
  • Usage: Supports Joint Health, Supports Healthy Cartilage
  • Safety: Harbel Ingredients
  • Refund Policy: 30-Day
  • Company Info: Pharmapacks, LLC 1516 Motor Pkwy, Islandia, NY 11749, +1-(888) 532-4574,
    SchiffCustomerCare@reckitt.com

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This stuff is amazing!

13 Best MSM Supplements for Inflammation and Joint Pain Relief (66)
“This product was recommended by a nurse friend of mine for joint and arthritis pain. I suffer from fibromyalgia and have arthritis in my hands and hips. I started out taking one a day and have ramped up to two a day over time. While it doesn’t eliminate flaring or the conditions themselves, it is the only non-pain relief drug I’ve ever taken that significantly helped me. And no stomach upset or smell. Id recommend it highly. 6 people found this helpful.”– kaira

Move Free Joint Health Advanced Plus MSM is a dietary supplement designed to support joint health and reduce joint discomfort. It is made by Schiff, a well-known manufacturer of health and wellness products.

“Glucosamine hydrochloride is a popular supplement for treating joint pain, and it may be beneficial for improving joint function in people with osteoarthritis.” , says Dr. David Pisetsky, Rheumatologist

The supplement contains a combination of ingredients, including glucosamine, chondroitin, MSM (methylsulfonylmethane), hyaluronic acid, and Uniflex. Together, these ingredients work to promote joint mobility, flexibility, and comfort. They may also help to support overall joint health and prevent the breakdown of cartilage.

Official Website

13 Best MSM Supplements for Inflammation and Joint Pain Relief (67)

Osteo Bi Flex Triple Strength | Best Pills For Joint Pain

13 Best MSM Supplements for Inflammation and Joint Pain Relief (68)

Osteo Bi Flex Triple Strength MSM With D3

13 Best MSM Supplements for Inflammation and Joint Pain Relief (69)

(3.1/5) 187 REVIEWS

$59.00AMAZON

PRODUCT SPECIFICATIONS

  • Form: Tablet
  • Quantity: 200 Tablet
  • Brand: Osteo Bi-Flex
  • Dosage: 2 Tablets Per Day
  • Ingredients: Glucosamine, MSM, Joint Shield 5-Loxin Advanced
  • Usage: Support Healthy Connective Tissue and Joint Cartilage
  • Safety: Gluten Free, Harbel Ingredients
  • Refund Policy: 60-Day
  • Company Info: The Bountiful Company Legal Department 60 Orville Drive Bohemia, New York 11716

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Works for joint pain and soft tissue repair.

13 Best MSM Supplements for Inflammation and Joint Pain Relief (71)
“I broke my knee meniscus in the gym, either due to squats or god knows what else. The physiotherapist told me that this is a connective tissue and cartilage injury that will be recovered in a few months. I started taking bone broth and other collagen-based drinks. These capsules were God-sent in Severe Pain Days. I still take them for backache and knee pain. They might give you some bloating, so take fibre.”– Jenn M.

Osteo Bi-Flex Triple Strength MSM with D3 is a dietary supplement that promotes joint health and flexibility. It contains key ingredients such as glucosamine, chondroitin, MSM (methylsulfonylmethane), and vitamin D3[6]. These ingredients collaborate to improve joint comfort and mobility, reduce inflammation, and promote bone health.

Osteo Bi-Flex is the best dietary supplement for healthy joints and cartilage. It contains 1,500 mg of glucosamine, a necessary component of cartilage, as well as Joint Shield, a special joint health blend that also contains chondroitin, MSM, and our proprietary 5-Loxin Advanced. Osteo Bi-Flex is the only product line that offers Joint Shield, which aims to prevent the action of enzymes that harm joint health. It improves joint mobility and strength.

Official Website

What Is MSM Supplement?

We should really start out by looking at what MSM is. As we have already noted, MSM is short for methylsulfonylmethane.

According to WebMD, MSM is a natural substance. It is already found within the human body, which really makes sense that the supplement may be beneficial for improving certain functions in the human body.

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In addition to being found within the human body, MSM is also found in some plants and in animals. It is also reported that MSM is usually taken as a supplement to assist in improving joint pain , especially amongst patients who have been diagnosed with arthritis.

Today, the most common form of MSM is created in a laboratory. It should be noted that in recent times, MSM is often combined with other ingredients in order to create a more potent and effective solution. Some of these ingredients usually include:

  • Chondroitin
  • Glucosamine

Thing To Consider Before Buying MSM Supplement

When buying MSM supplements, there are several things to keep in mind to ensure that you receive a safe and effective product. Here are some essential considerations:

Purity and Quality

Look for an MSM supplement from a reputable brand that adheres to strict manufacturing and quality control standards. Choose a product that has been tested for purity and potency by a third party.

Dosage

The recommended MSM dosage varies depending on the individual and the condition being treated. Choose a supplement with a dosage that meets your needs and consult with a healthcare provider to determine the appropriate dose for you.

Ingredients

Some MSM supplements may contain additional ingredients that are beneficial to joint health, such as glucosamine or chondroitin. Check the label to make sure any additional ingredients are safe and suitable for you.

Form

MSM is available in various forms, including capsules, powders, and creams. Choose the form that is most convenient and comfortable for you to use.

Allergies and Sensitivities

If you are allergic or sensitive to certain ingredients, read the label carefully and avoid any supplements that contain those ingredients.

Brand Reputation and Customer Reviews

To ensure that you are getting a high-quality product, look for MSM supplements from reputable brands with positive customer reviews.

Overall, it is important to consider the above factors before purchasing an MSM supplement. Before initiating any new supplement regimen, consult with a healthcare provider.

What Are The Benefits Of Methylsulfonylmethane Supplements?

Now that we have looked at what MSM is, let’s focus on the benefits that this particular substance is able to offer a user when it is taken as a supplement on a regular basis.

As we have explained before, the most popular use of MSM is amongst arthritis patients as it is known that this substance is able to provide effective relief of common arthritis symptoms.

“MSM is a sulfur-containing compound that is required for the formation and maintenance of healthy connective tissues. MSM has been shown to reduce inflammation and pain in people with osteoarthritis and other inflammatory conditions when taken as a supplement.” , saysDr. Josh Axe, D.N.M., C.N.S., D.C.

While these are commonly known facts, we should mention that MSM has some additional benefits that aren’t always apparent; let’s take a look at these.
The Model Health Show explains that some of the most important benefits of MSM to be considered include:

  • Anti-inflammatory – This is one of the most potent benefits of MSM, and is not only useful when it comes to joint inflammation, but also when inflammation occurs throughout the rest of the body.
  • Elimination – MSM can help the body speed up the elimination process of waste. The substance is so effective that it can even remove waste from the body’s cells. In turn, this can greatly increase the rate at which the body is able to heal itself after injury.
  • Detoxification – In addition to providing an effective way to remove waste from the body, we should also note that MSM has been proven to detoxify the body as well. MSM is a type of calcium phosphate dissolver which means it is able to assist with the breakup of certain types of calcium that are harmful to the body. This type of calcium is known to greatly contribute to degenerative diseases; eliminating the substance from the body can help to slow down the progression of such diseases considerably.
  • Flexibility – Some evidence has suggested that MSM is also useful in improving overall flexibility of the joints. This is another excellent benefit since individuals suffering from joint pain , especially arthritis-related, tend to experience a significant reduction in flexibility and range-of-motion.

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Can MSM Supplements Help You Relieve Joint Pain?

By looking at the benefits of MSM we have discussed above, it should be obvious that MSM can, indeed, be helpful in relieving joint pain, as well as other accompanying symptoms.

Flexibility can be increased through the use of this supplement, and inflammation can be significantly reduced. The big question, however, is whether or not any clinical evidence is available to prove the efficiency of MSM for joint-related symptoms.

According to Arthritis Research UK, several scientific studies have pointed out that MSM possesses anti-inflammatory properties, as well as potent antioxidant effects within the human body. The substance is rich in sulfur, which means it is able to assist with the production of glucosamine and collagen in the body.MSM is a form of sulfur that is important for many biological processes in the body, including the maintenance of healthy joints, skin, and hair.

MSM is known for its anti-inflammatory properties and is often used to reduce joint pain and stiffness. It is also used to improve the health of skin and hair as it’s an essential part of collagen, a protein that gives skin and hair strength and elasticity. It also helps the immune system function by reducing inflammation and oxidative stress in the body.

These two substances contribute to improvements in overall joint health, which in turn help relieve arthritis symptoms , as well as the detrimental effects on joints throughout the body.

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Product Comparison

To help you decide, here is a brief comparison of our top picks:

JointXL PlusProJoint PlusMicro Ingredients MSM PowderNOW MSM PowderDoctor’s Best MSM with OptiMSM
Rating13 Best MSM Supplements for Inflammation and Joint Pain Relief (75)13 Best MSM Supplements for Inflammation and Joint Pain Relief (76)13 Best MSM Supplements for Inflammation and Joint Pain Relief (77)13 Best MSM Supplements for Inflammation and Joint Pain Relief (78)13 Best MSM Supplements for Inflammation and Joint Pain Relief (79)
Cost$54.00$29.95$21.95$16.53$22.98
Dosage6 Capsules Per Day3 Capsules Daily1 Scoop Per Day2 Teaspoon Twice in a Day3 Capsules Per Day
UsageEnhances Comfort, Mobility & FlexibilitySupports Joint and Cartilage HealthSupport Ultimate Joint FunctionSupports Healthy CartilageSupport Joint Comfort and Mobility
Return Policy60-Day30-Days30-Day30-Day60-Day
ProsLaboratory Tested IngredientsNo Prescription RequiredNon-GMO, Organic IngredientsDairy Free, Soy FreeNon-GMO, Gluten Free
ReviewAll in One Joint SupplementNoticeable ImprovementReasonable Deal.Result – Time ConsumingHighly Expensive
Shop Now

Frequently Asked Questions

Q. How to use MSM supplements for reducing joint-related symptoms?

A:MSM is available in various forms for the convenience of the user. The most common way to use MSM is to buy a supplement that contains this particular substance. There are numerous products that contain MSM as the only ingredient for people who like to take their supplements individually.

There are also a large number of supplements that combine MSM with other ingredients, making the formula even more effective for reducing arthritis symptoms .

MSM can also be purchased in powdered form, which can be added to food or, in some cases, mixed with water and taken as a drink.

Q. Is it safe to use MSM supplements?

A: The safety of natural joint pain supplements is often a concern amongst the general population who wish to use them. Fortunately, the safety of MSM has been tested in several clinical trials and scientific studies in order to determine whether MSM may be toxic to a user or cause any serious side-effects.

These studies found that MSM is very safe to use as a daily supplement to assist with managing the symptoms of arthritis. The standard dosage that was tested for MSM amongst arthritis patients was 1,500mg a day, but there have been other studies suggesting 2,600mg on a daily basis is also relatively safe.
The only side effects that have been reported amongst individuals who have used MSM for the treatment of arthritis or any of the other benefits on offer was mild discomfort in their gastrointestinal tract.
Furthermore, no interactions have yet been reported, which means MSM is not likely to cause any problems when used with other types of medication.

Q. What are the dangers of MSM?

A: MSM is generally considered safe when taken as directed. Several studies have concluded that taking 4,845.6 mg of MSM daily is safe. However, it may cause side effects or interact with other medications or medical conditions, just like any other supplement or medication.

When applied to the skin, it can cause skin irritation as well as nausea and bloating. Furthermore, because alcohol contains sulphur, it should be avoided when combined with MSM supplements.

Q. What do MSM supplements do to the brain?

A: So far, there is no evidence that it is harmful to the brain. It does cross the blood-brain barrier (a network of blood vessels and tissue that helps keep harmful substances reaching the brain)but no studies have been conducted to determine its effect.

Q. When should I take MSM supplements?

A: This will depend on the brand recommendation as the instructions will differ with each product You can also ask your doctor or a healthcare professional for advice on the best time to take an MSM supplement.

Final Thought

Joints are important for the overall function of the human body, and allow us to move about during our daily lives, care for our families, work and more.

Unfortunately, many people experience a significant number of side-effects when they use conventional treatment options to treat their joint conditions. Luckily, alternative options are available to provide a relief of symptoms without experiencing unwanted side-effects.

In this post, we have taken a look at how MSM can be helpful in providing relief from joint pain, as well as considering some additional substances that may be useful in treating joint pain naturally. We also provided a variety of MSM supplements that you can start using today to help ease the symptoms you may be currently experiencing.

Why Trust CHD?

Robert G. Silverman is the founder of the Westchester Integrative Health Centre and specialises in treating joint pain using functional nutrition and cutting-edge science-based nonsurgical approaches. He is an expert in his field and practice. To review this article, he read through the ratings, results, online reviews, and user experiences. He rated each product based on its ingredients, benefits, price, and reviews. He has been associated with consumer health issues for several years. He consulted with Dr. David Felson, an associate professor of medicine and epidemiology at the Boston University School of Medicine.

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Louise is a Registered Nurse who completed her education in the UK. She transferred her nursing licenses to the US and subsequently com Read Full Bio

6 Sources

We review published medical research in respected scientific journals to arrive at our conclusions about a product or health topic. This ensures the highest standard of scientific accuracy.

[1] Henrotin Y, Mathy M, Sanchez C, Lambert C. Chondroitin sulfate in the treatment of osteoarthritis: from in vitro studies to clinical recommendations. Ther Adv Musculoskelet Dis. 2010 Dec;2(6):335-48. doi: 10.1177/1759720X10383076. PMID: 22870459; PMCID: PMC3383492.
[2] Carr AC. A new clinical trial to test high-dose vitamin C in patients with COVID-19. Crit Care. 2020 Apr 7;24(1):133. doi: 10.1186/s13054-020-02851-4. PMID: 32264963; PMCID: PMC7137406.
[3] Shaw G, Lee-Barthel A, Ross ML, Wang B, Baar K. Vitamin C-enriched gelatin supplementation before intermittent activity augments collagen synthesis. Am J Clin Nutr. 2017 Jan;105(1):136-143. doi: 10.3945/ajcn.116.138594. Epub 2016 Nov 16. PMID: 27852613; PMCID: PMC5183725.
[4] Bowman S, Awad ME, Hamrick MW, Hunter M, Fulzele S. Recent advances in hyaluronic acid based therapy for osteoarthritis. Clin Transl Med. 2018 Feb 16;7(1):6. doi: 10.1186/s40169-017-0180-3. PMID: 29450666; PMCID: PMC5814393.
[5] Butawan M, Benjamin RL, Bloomer RJ. Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement. Nutrients. 2017 Mar 16;9(3):290. doi: 10.3390/nu9030290. PMID: 28300758; PMCID: PMC5372953.
[6] Putman MS, Pitts SA, Milliren CE, Feldman HA, Reinold K, Gordon CM. A randomized clinical trial of vitamin D supplementation in healthy adolescents. J Adolesc Health. 2013 May;52(5):592-8. doi: 10.1016/j.jadohealth.2012.10.270. Epub 2012 Dec 23. PMID: 23608721; PMCID: PMC3634127.

**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

*Result may vary. If you are pregnant, nursing, have a serious medical condition, or have a history of heart conditions we suggest consulting with a physician before using any supplement. The information contained in this website is provided for general informational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be relied upon as a medical advice. Always consult your doctor before using any supplements.

Disclosure of Material connection: Some of the links in the post above are "associate sales links." This means if you can click on the link and purchase an item, we will receive a commission. Regardless, we only recommend products or services which we use personally and/or believe will add value to our readers. We are disclosing this in accordance with the Federal Trade Commission's 16 CFR, Part 255: "Guides Concerning the Use of Endorsem*nts and Testimonials."

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